Sunday 7 April 2024

29M quantified self PaJR

PaJR = patient journey record where patient advocate share a patient's updates according to guidance they get from their primary care provider who is supported by a group of volunteer medical professionals (ranging from medical innovators who may be engineers and  medical students, to residents and consultants. Basically a knowledge network). [Currently Implemented as a whatsapp group]

The patient advocate ensures privacy, data management, and continuity of care.

The updates are:

- lifestyle modification related eg. Calorie deficit

- medication adherence related,

- patient education queries,

etc.



The current case is a 29 year old otherwise healthy but obese man having weight of 86.5-87 kg even after being physically active. His height is 5 feet 5 inches, BMI is 32 and below is picture from Google fit (mobile) data about his daily walk (since many months his average is 5km daily).





All the analytics and charting below is done with help of ChatGPT (free version) and google collab (to run python code output given by chat gpt).


Estimated Basal Metabolic Rate (BMR) for this 29-year-old obese man is approximately 1877.22 kcal/day. 


For 1 month of calorie deficit (31 days)  patient maintained average daily total walk of 5km. Checked weight nearly every week - 86.5, 85, 84, 83, 82.5.


These are his daily calorie intake for 31 days. (Calorie counting done manually by patient advocate. )


1. 600 kcal

2. 750 kcal

3. 1200 kcal

4. 1000 kcal

5. 1100 kcal

6. 800 kcal

7. 900 kcal

8. 1700 kcal

9. 1300 kcal

10. 1400 kcal

11. 2000 kcal

12. 1500 kcal

13. 1250 kcal

14. 1500 kcal

15. 1800 kcal

16. 1450 kcal

17. 1150 kcal

18. 1400 kcal

19. 1450 kcal

20. 1500 kcal

21. 1800 kcal

22. 1500 kcal

23. 1400 kcal

24. 1300 kcal

25. 1200 kcal

26. 1250 kcal

27. 1700 kcal

28. 1900 kcal

29. 1150 kcal

30. 1000 kcal

31. 1350 kcal




Patient used to take around 2500 kcal daily before starting intervention. 


Here are some useful graphs. (The data is in reverse order in these graph 1, 2, & 4).







ChatGPT - One fascinating insight from this reverse order calorie counting data is the oscillation between higher and lower calorie days. By visualizing this data as a sine wave graph, with each day represented as a point along the curve, we see a rhythmic pattern emerge. The peaks and troughs represent days of higher and lower calorie intake respectively, creating a visually stunning wave pattern that illustrates the natural ebb and flow of dietary habits. This visualization highlights the balance between indulgence and restraint, offering a captivating depiction of the intricate dance of calorie consumption over time.




In simple words

- trend is useful to see it started Aggressive and plateau at around 1500 kcal
- seasonal indicate that after getting more strict patient is going back to less strict by variation of around -200 to +200 kcal range.

(Dates are incorrect in this graph).


This data also helps to predict calorie intake for next day it may have high inaccuracy. Regression analysis predicted next day calorie intake to be 1561 kcal.


Useful motivating / behavioural nudging messages are also possible which may also have good information to help reduce junk food intake by awareness. Like -

Day 1 - 600 calories intake: Equivalent to approximately 0.7 liters of petrol or 1.3 servings of chowmein.


Day 31 - Calorie deficit: 2500 - 1350 = 1150 calories

1) Equivalent to approximately 10,000 steps of brisk walking.

2) Equivalent to 45 minutes of high-intensity interval training (HIIT).



Requesting to share if any inputs/corrections in comment section below this blog post.

You may also like to check my precious work about fever charts here - https://classworkdecjan.blogspot.com/2021/02/some-tech-for-just-fever-sign.html

Wednesday 28 February 2024

A Session on Teaching critical appraisal for medicos and non-medicos

A Session on Teaching critical appraisal for medicos and non-medicos ( part 1)


(Part 2.0, 2.1, 2.2, and so on.. will be my blogs/links to student blogs having real patient with real problem having done critical appraisal. Feel free post link to your blog in comment section if you do this exercise.)


The key difference for medicos and non-medicos is just about the knowledge base.

A non medico person may know less than a non medico patient, A non medico patient may know less than a medico, a medico may know less than a specialist, and a specialist may know less than a medico patient (or a self taught & empowered patient citizen scientist)

So, as we begin learning *critical appraisal* so we can progress further to practice and develop skill in it to be good at *evidence based medicine*

My first question is, should there be learning of medicine without a patient at the center of the exercise?

No. I guess, everyone agrees.

So, let's start with the person at center. A person who may be sick and so came to us to provide us a learning opportunity.

We have a video about patient as a teacher, as all patients are our teachers giving us, the medico fraternity, lifelong learning opportunities. It's not important watch the video right now, but it have a glimpse of everything we are going to learn ahead.

https://youtu.be/xvE5b8Xk3vM?si=2GE-4ehkcO8Whmjo

A person is there with us now. We need to know their problems. Is that all?

No. We need to make them comfortable, be empathetic, respectful, make them feel supported, etc etc. Refer to AETCOM.

So, the first step for active learning - *taking patient history*

History is story of the patient.  It can be taken as taught in medical school to take in detail, or can be in narrative format which is easier for non-medicos and even medico newbies. A good history can be detailed, with a timeline, from reliable source/sources, etc. Refer to any clinical medicine book and you will find more in initial chapters. Patient problems can be detailed

- qualitatively (eg. shooting pain), 


- quantitatively (eg. 100 degree temperature),


- narrative way (eg. paining so badly since morning that unable to do household work).

Updating patient history with time is important, and you must note that a good patient history (data capture) is extremely useful and most important part of our efforts.

Step 2 is *clinical examination* (look, feel, touch, etc. Refer to any clinical medicine book to learn more)

You can also take pictures, record audio/video, etc.

With history and examination alone, most of diseases happening to mankind can be identified.

Next step is investigations as they help us conform our provisional diagnosis, and look more deeply into the human body to get clear picture of the problems.

All these cover 2 important concerns for our patient.

- *What is the problem* (listen)


- *Where is the problems* (examine)

Now, as we go to the next patient concern, we gets our hands dirty into EBM. But wait, was taking history and examination were not EBM? They were. The examinations have their sensitivity, specificity, protocols, etc. The history taking helps us understand patient priorities and lot more.

So the next concern is

- *what can be done about it*

Or the treatment plan, or the questions that we may get from our patient or ourselves when trying to create a robust treatment plan.

Before diving deep into it, let me first tell you about

- *SOAP notes*


- *PaJR*


- Identifying fake news.

*SOAP notes*.

SOAP means Subjective, Objective, Assessment and Plan.

It's a way of documentation and hence communication, for medical team providing care.

To simplify,

S means write in your narrative way about what is patient concern today/now.

O means write objective values like temperature readings, investigation outcomes, etc.

A means your observation/examination/assessment of the patient now.

P treatment plan.

So as a medico/non-medico/patient/caretaker you can also follow this template for recording daily data. Detailed and good data is important.

*PaJR* - patient journey record. The concept is applied in many way, but what I want to convey is, you can document the patient's journey as

daily patient update + picture of their food plates + sleep routine + exercise routine etc. Can add as many parameters as patient and you want but keeping it focused on clinically meaningful parameters relevant to patient may increase adherence to regularly updating data.

*Identifying fake news*

How can you do it? Fake news are so common that there is a term for it now called infodemic. I think you may be already doing it by

1) checking the news to know if it's not a clickbait

2)checking same news from multiple source.

3) checking news from authentic and more reliable source.

So, by doing any of these steps, you kept skepticism and didn't accept the information as it is, and also you critically analysed it to confirm it's authenticity. This is an example of critical appraisal of information. We are going to do same for medical evidence published in research papers. It's going to be exciting.


EBM is not just the information from best research.


When we look into research, these are types of clinical research studies. There are invitro and invivo studies at pre-clincial levels too. They can go at the bottom below the pyramid. The pyramid gives an idea about levels of clinical usefulness of type of study but it must not create an illusion that something at lower levels is useless in comparison to something at higher level, as every study type have it's pros and cons and so all have their importance and the raking gets blurred.


Even a type of research study can have sub types, having it's own pros and cons.

Eg. For clinical trials

Above 3 images gives basic idea for anyone to go ahead. It's advised to dive deeper as you learn by doing critical appraisal of evidence around clinical questions.

So, I will first share the easy way of critical appraisal and then I will also share the hard way.

Easy way is quick and gives important details. Hard way is time consuming and gives more understanding.

Here comes the easy way -

- identify the type of study (in research paper you are going to practice critical appraisal)


- download the critical appraisal tool for that type of study, from any of these websites and try it.

https://www.cebm.ox.ac.uk/resources/ebm-tools/critical-appraisal-tools

https://casp-uk.net/casp-tools-checklists/

(There are many, can search on internet "critical appraisal tools")

The easy way can get you started quickly, the hard way is to go through paper in detail, look for data and statistical analysis in detail, look for even the data about individual patients, look for possible biases and fundings, etc. It may be overkill sometimes.

Pro tip - various CDSS apps (clinical decision support system) are available that have pre-appriased evidence summaries to common clinical questions.

Ohh, are we missing something?

Yes..  The clinical question..or we are also missing the patient.. damn..that is what happen frequently in medical education where the key beneficiary goes out of the picture, that's so bad.. 

Let's stop here and I give you home work to

1) bring your patient to us by sharing the patient story and findings (or can also say it history and examination) in form of a blog where you have consent from the patient for doing it and whole of it is properly de-identfied.

2) share patient's/your clinical questions so we can start looking into evidence for it.

If you want an example case record, here it is - https://classworkdecjan.blogspot.com/2019/05/42-f-with-severe-regular-edema-with_17.html

Pro tip - there is a giant website where we can search most of medical research papers. https://pubmed.ncbi.nlm.nih.gov/ (Googling is not a bad idea though)

https://classworkdecjan.blogspot.com/2017/11/de-identifying-patient-data.html